Skip to content

1,4-Dihydroxybenzene (Hydroquinone), with the exception of entry 14 in Annex III

CAS 123-31-9
12

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A cosmetic ingredient. Exercise caution due to limited available safety data.

1,4-Dihydroxybenzene (Hydroquinone) is banned in cosmetic products under EU Annex II of Regulation (EC) No 1223/2009 (entry 1339). It is classified as carcinogenic (H351), mutagenic (H341) and a skin sensitiser (H317) under the CLP Regulation. Its use is strictly limited to artificial nail systems under highly controlled conditions. Any cosmetic product containing hydroquinone is non-compliant with EU law.

Known concerns

  • EU Annex II banned substance (entry 1339)
  • Carcinogenic (H351) and mutagenic (H341)
  • Severe skin sensitiser (H317)
  • Ochronosis with prolonged use
  • Eye and organ toxicity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Check your shelf

Find 1,4-Dihydroxybenzene (Hydroquinone), with the exception of entry 14 in Annex III in your products.

Scan any cosmetic product with LuxSense to see if it contains 1,4-Dihydroxybenzene (Hydroquinone), with the exception of entry 14 in Annex III and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.