2-Phenylindan-1,3-dione (Phenindione (INN))
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
2-Phenylindan-1,3-dione (Phenindione (INN)) is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.
2-Phenylindan-1,3-dione (Phenindione) is an indanedione anticoagulant drug (vitamin K antagonist) with pharmacological activity that makes it completely unsuitable for cosmetic application. It carries H301 (acute toxicity) and H317 (skin sensitizer) classifications. Its primary use is as a rodenticide and pharmaceutical anticoagulant, not cosmetics. The compound is not listed in EU cosmetic regulation Annexes but is clearly contraindicated by its pharmacological nature and toxicity profile.
Known concerns
- Acute oral toxicity (H301)
- Skin sensitizer (H317)
- Pharmacological drug activity (anticoagulant)
- Not suitable for cosmetic use
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.