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Acetone oxime

CAS 127-06-0
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A chemical intermediate used in industrial applications including resin synthesis and as an antioxidant. Its use in cosmetics is limited, and it carries some skin absorption concerns.

Acetone Oxime (also called 2-propanone oxime or acetoxime; CH3-C(=NOH)-CH3) is formed from the reaction of acetone with hydroxylamine. It is used as an intermediate in chemical synthesis, particularly in the manufacture of pesticides and pharmaceuticals, and as an antioxidant and corrosion inhibitor. Skin absorption has been documented, and it may cause mild skin sensitization. IARC has not classified acetone oxime for carcinogenicity, but its primary uses are industrial rather than cosmetic. Limited data exist for long-term topical cosmetic use.

Skin benefits

  • May function as an antioxidant in formulations
  • Limited documented skin benefits in cosmetic context

Known concerns

  • Skin absorption documented
  • Mild skin sensitization potential
  • Limited long-term cosmetic safety data
  • Industrial chemical with limited cosmetic history

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.