Acetylcholine
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
An endogenous neurotransmitter that is biologically active but rapidly degraded, with limited direct cosmetic application.
Acetylcholine is a naturally occurring neurotransmitter that acts at muscarinic and nicotinic receptors, playing key roles in neuromuscular junctions and parasympathetic signaling. While the body produces it endogenously and it has low direct toxicity, it is extremely unstable in aqueous solution and rapidly hydrolyzes. Its pharmacological activity makes it unsuitable as a functional cosmetic ingredient, and it is not listed in EU-approved cosmetic ingredient databases.
Known concerns
- Pharmacologically active (muscarinic/nicotinic effects)
- Extremely unstable in aqueous formulation
- Not listed as approved cosmetic ingredient in EU
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.