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Banned neurotransmitter

Acetylcholine

CAS 51-84-3
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Acetylcholine is the body's natural nerve-signal molecule. It is banned from cosmetics in the EU because it is a pharmacological neurotransmitter rather than a true skincare ingredient.

Skin benefits

  • Endogenous neurotransmitter, theoretical signaling research interest
  • No established cosmetic functional benefit

Known concerns

  • Acetylcholine is a pharmacologically active neurotransmitter
  • EU Annex II lists acetylcholine and its salts as banned cosmetic substances
  • Risk of unintended systemic neurological effects
  • Stability and unsuitable mode of action for cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.