AZULENE
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A deep-blue aromatic compound found in chamomile and yarrow — prized in skincare for its powerful anti-inflammatory and soothing effects, though it can be a sensitizer for some.
Azulene (C15H18) is a bicyclic sesquiterpene — technically a derivative of guaiazulene, not a true azulene. It is responsible for the deep blue color of chamomile (Matricaria chamomilla) and Achillea millefolium (yarrow) essential oils. Azulene is a potent inhibitor of COX-2 and prostaglandin synthesis, making it highly anti-inflammatory. However, it can act as a contact sensitizer in susceptible individuals and is restricted in some jurisdictions due to potential health effects from certain manufacturing processes (associated with ozone-depleting substances in older extractions). The EU restricts some azulene-related compounds; caution warranted in sensitized individuals.
Function
Skin benefits
- Anti-inflammatory
- Soothing for irritated skin
- Antioxidant
- Calming for敏感肌肤
Known concerns
- Contact sensitization in susceptible individuals
- Restricted in some markets due to ozone-layer concern in extraction processes
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Check your shelf
Find AZULENE in your products.
Scan any cosmetic product with LuxSense to see if it contains AZULENE and get a full ingredient breakdown with safety scores.
This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.