AZULENE
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A deep-blue aromatic compound found in chamomile and yarrow — prized in skincare for its powerful anti-inflammatory and soothing effects, though it can be a sensitizer for some.
Azulene (C15H18) is a bicyclic sesquiterpene — technically a derivative of guaiazulene, not a true azulene. It is responsible for the deep blue color of chamomile (Matricaria chamomilla) and Achillea millefolium (yarrow) essential oils. Azulene is a potent inhibitor of COX-2 and prostaglandin synthesis, making it highly anti-inflammatory. However, it can act as a contact sensitizer in susceptible individuals and is restricted in some jurisdictions due to potential health effects from certain manufacturing processes (associated with ozone-depleting substances in older extractions). The EU restricts some azulene-related compounds; caution warranted in sensitized individuals.
Function
Skin benefits
- Anti-inflammatory
- Soothing for irritated skin
- Antioxidant
- Calming for敏感肌肤
Known concerns
- Contact sensitization in susceptible individuals
- Restricted in some markets due to ozone-layer concern in extraction processes
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.