BIFONAZOLE
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
An imidazole antifungal agent originally developed as a pharmaceutical for topical fungal infections that is not approved as a cosmetic preservative or active ingredient in the EU, with limited safety data for cosmetic formulation.
Bifonazole is a broad-spectrum imidazole antifungal used in pharmaceutical creams for the treatment of tinea and candidiasis. While imidazole antifungals are generally well-tolerated in topical pharmaceuticals, bifonazole specifically is not listed in EU CosIng for cosmetic use. The imidazole ring can act as a histamine releaser and may cause local skin reactions.
Skin benefits
- Pharmaceutical: broad-spectrum antifungal useful for treating fungal skin infections
Known concerns
- Not listed in EU CosIng for cosmetic use
- Imidazole ring may cause histamine release and local skin reactions
- Pharmaceutical-grade active not appropriate for cosmetic formulations without safety data
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.