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Photoinitiator (under review)

BIS-TRIMETHYLBENZOYL PHENYLPHOSPHINE OXIDE

CAS 162881-26-7
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A phosphine oxide photoinitiator used in UV gel nail products to harden polymers under UV/LED light; recently classified as a suspected reproductive toxicant, prompting EU regulatory restrictions.

Skin benefits

  • Photoinitiator used in UV-cured gel nail products
  • Enables fast curing of nail gels under LED/UV light
  • Provides hard, durable gel finishes
  • Effective at low concentrations

Known concerns

  • BAPO is classified as suspected reproductive toxicant (Repr. 1B) in EU CLP
  • EU has proposed restrictions and may classify it as CMR with Annex II implications
  • Cases of contact allergy and onycholysis reported from improperly cured nail gels
  • Sensitization risk for nail technicians with chronic exposure

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.