BIS-TRIMETHYLBENZOYL PHENYLPHOSPHINE OXIDE
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A photoinitiator compound used in nail gel and UV-cured cosmetic formulations to trigger polymerization when exposed to UV light. Known to generate reactive oxygen species, which is the main concern for skin safety.
Bis-Trimethylbenzoyl Phenylphosphine Oxide (BTMPO) is a phosphine oxide-type photoinitiator used in UV/LED-curable cosmetic systems, particularly in nail gels and resin-based products. When irradiated with UV light (365-405 nm), it generates free radicals that initiate acrylate polymerization. The compound has good photoinitiation efficiency but can leach from cured matrices over time. The main safety concern is its potential to generate reactive oxygen species (ROS) upon UV exposure, leading to oxidative skin stress. EU cosmetics regulation requires appropriate warning labels for products containing this substance.
Skin benefits
- Enables fast UV-curing of nail gel formulations
- Provides durable, glossy finish in cured nail coatings
Known concerns
- Photosensitization — generates ROS under UV exposure
- Potential skin allergen in uncured form
- May cause irritation if leached from cured products
- EU regulated for nail product use
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.