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Banned solvent

BUTYROLACTONE

CAS 96-48-0
18

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Gamma-butyrolactone is a controlled GHB precursor banned from EU cosmetic use. It poses serious systemic toxicity risk and is prohibited under the Cosmetics Regulation Annex II.

Skin benefits

  • Used industrially as a solvent for polymers and as a chemical intermediate
  • Has applications in pharmaceutical synthesis

Known concerns

  • Gamma-butyrolactone is a controlled precursor of GHB with serious abuse potential
  • Listed under EU Annex II of Cosmetics Regulation as prohibited
  • Causes central nervous system depression on systemic exposure
  • Skin and eye irritant requiring industrial handling controls

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related banned solvents

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.