Cyclic 3-(1,2-ethanediylacetale)-estra-5(10),9(11)-diene-3,17-dione
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.
This bridged estrane derivative with 3,17-dione functionality is a synthetic steroid hormone analog with documented endocrine-disrupting and carcinogenic potential. Its multiple hazard statements (H302, H350, H351, H360F, H361, H373, H411, H413) cover the full spectrum of EU CMR substance concerns. It is listed under EU Annex II as a prohibited CMR substance for all cosmetic product types, with zero tolerance in finished products.
Known concerns
- Carcinogen (H350)
- Suspected carcinogen (H351)
- Reproductive toxicity (H360F, H361)
- Acute oral toxicity (H302)
- Endocrine-disrupting steroid
- Banned CMR substance in EU Annex II — prohibited in all cosmetic products
- Environmental hazard (H411, H413)
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.