DISODIUM GUANYLATE
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
The disodium salt of guanylic acid — a nucleotides used in cosmetics primarily for flavor enhancement in oral care products, though it also provides some skin-conditioning benefits.
Disodium Guanylate (GMP, disodium guanosine-5'-monophosphate) is the sodium salt of guanosine-5'-monophosphoric acid. It is a flavor enhancer commonly used in conjunction with disodium inosinate in culinary and oral care applications. In skincare, it functions as a skin-conditioning agent. Guanylic acid is naturally occurring and poses no significant toxicity. It is not listed in EU Annexes II or III as restricted or banned, and shows no sensitization or irritation concerns at cosmetic-use concentrations.
Skin benefits
- Skin-conditioning — supports skin texture
- Nucleotides are natural cellular components with generally benign profiles
Known concerns
- Primarily relevant for oral care/flavor applications — limited concern in skin formulations
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.