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DISODIUM SITOSTERETH-14 SULFOSUCCINATE

CAS 206659-83-8
85

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Disodium Sitostereth-14 Sulfosuccinate is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

This is one of the more distinctive ingredients in this batch — a sulfosuccinate where the alkyl chain is a stigmast-5-en-3-beta-yl (sitosteryl) group, essentially a phytosterol. Plant sterols like sitosterol are structurally similar to skin lipids (including cholesterol) and integrate well with the skin barrier, potentially enhancing tolerability. The 14-mol EO group provides substantial water solubility. Sitosterol-derived ingredients are not restricted under EU Regulation (EC) No 1223/2009. Phytosterols themselves have a strong safety record in topical applications and are actually beneficial for skin barrier function.

Skin benefits

  • Sitosterol moiety is barrier-compatible and may reinforce the stratum corneum
  • High EO chain provides excellent water solubility and formulation flexibility

Known concerns

  • Complex structure means more extensive purification may be required during manufacturing
  • Very high EO (14 mol) — residual 1,4-dioxane requires standard monitoring

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.