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Fludrocortisone

CAS 127-31-1
10

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Fludrocortisone is a cosmetic ingredient. Exercise caution due to limited available safety data.

Fludrocortisone acetate is a synthetic corticosteroid with potent mineralocorticoid activity (approximately 100 times more than hydrocortisone) used in treating adrenal insufficiency. It is prohibited in cosmetic products under EU Cosmetics Regulation Annex II. Hazards include acute toxicity (H302, H312, H332), skin and eye irritation (H315, H319), H335 (respiratory irritation), and H361 (suspected reproductive toxicity).

Known concerns

  • Banned in EU cosmetic products (Annex II)
  • Potent mineralocorticoid activity
  • Acute toxicity (H302, H312, H332)
  • Reproductive concern (H361)
  • Skin and respiratory irritation (H315, H319, H335)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.