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Skin Conditioning

GLYCERYL DIRETINOATE

Updated
22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A glycerol diester of retinoic acid. Retinoic acid (tretinoin) is a prescription drug in the EU and a known teratogen — its esters in cosmetics raise serious regulatory and safety concerns.

Function

SKIN CONDITIONING - MISCELLANEOUS

Skin benefits

  • Theoretical retinoid skin renewal benefits
  • Gradual release of retinoic acid

Known concerns

  • Diester of retinoic acid (tretinoin) — pharmaceutical-grade actives not allowed in EU cosmetics
  • Potential teratogenicity from retinoic acid
  • Photo-instability and skin irritation
  • Not on EU CosIng approved list for direct cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.