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HUMAN ADIPOSE-DERIVED STEM CELL CONDITIONED MEDIA

50

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

The growth medium from cultured human fat-derived stem cells, containing mesenchymal stem cell secretions rich in regenerative and anti-inflammatory factors.

Human adipose-derived stem cell conditioned media is restricted under EU Annex II/416 for materials of human origin. Adipose tissue is typically sourced from liposuction surgical waste with donor consent. ADSC secretome is one of the better-characterised among stem cell media, containing growth factors (VEGF, HGF, FGF), cytokines and adipokines. The human source eliminates TSE risk, but pathogen screening and full traceability documentation are mandatory under EU requirements.

Skin benefits

  • ADSC secretome contains VEGF and HGF with angiogenic properties
  • Anti-inflammatory cytokines may benefit sensitive skin
  • Documented secretory profile makes it one of the better-understood stem cell media

Known concerns

  • EU Annex II/416 restriction
  • Pathogen screening from surgical tissue source mandatory
  • FBS in culture media raises animal by-product compliance
  • Batch variability from primary culture

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.