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HUMAN ADIPOSE STROMAL CELL/HUMAN HAIR DERMAL PAPILLA CELL CONDITIONED MEDIA

48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

The growth medium from co-cultured human fat stromal cells and hair follicle dermal papilla cells, combining two skin-relevant cell secretomes.

This combined conditioned media is regulated under EU Annex II/416 for materials of human origin. Co-culture of adipose stromal cells and dermal papilla cells may produce a mixed secretome with distinct bioactivity compared to single-cell media. Dermal papilla cells are specialized follicle fibroblasts that secrete hair growth-modulating factors. Both cell types require donor screening and consent, and the combined undefined secretome requires thorough safety evaluation before EU cosmetic use.

Skin benefits

  • Combines adipose stromal and dermal papilla secretions
  • May support both skin matrix and hair follicle health
  • Contains mixed growth factor profile

Known concerns

  • EU Annex II/416 restriction for both cell types
  • Dual pathogen screening requirements
  • Undefined combined secretome
  • FBS in culture media compliance required

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.