HUMAN ADIPOSE STROMAL CELL/HUMAN HAIR DERMAL PAPILLA CELL CONDITIONED MEDIA
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
The growth medium from co-cultured human fat stromal cells and hair follicle dermal papilla cells, combining two skin-relevant cell secretomes.
This combined conditioned media is regulated under EU Annex II/416 for materials of human origin. Co-culture of adipose stromal cells and dermal papilla cells may produce a mixed secretome with distinct bioactivity compared to single-cell media. Dermal papilla cells are specialized follicle fibroblasts that secrete hair growth-modulating factors. Both cell types require donor screening and consent, and the combined undefined secretome requires thorough safety evaluation before EU cosmetic use.
Skin benefits
- Combines adipose stromal and dermal papilla secretions
- May support both skin matrix and hair follicle health
- Contains mixed growth factor profile
Known concerns
- EU Annex II/416 restriction for both cell types
- Dual pathogen screening requirements
- Undefined combined secretome
- FBS in culture media compliance required
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Same plant / compound family
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.