Skip to content

HUMAN BONE MARROW MESENCHYMAL STEM CELL CONDITIONED MEDIA

48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

The growth medium from cultured human bone marrow mesenchymal stem cells, one of the most scientifically documented MSC secretomes available for cosmetic use.

Human bone marrow MSC conditioned media is restricted under EU Annex II/416 for materials of human origin. Bone marrow is the classic source of MSCs and has the most extensive scientific literature. The secretome is relatively well characterised, containing TGF-beta, HGF, IGF-1, VEGF and immunomodulatory cytokines. Bone marrow aspiration requires medical procedures and consent, making sourcing more complex than adipose tissue. The ingredient is considered one of the stronger candidates among restricted human cell media for EU-compliant cosmetic applications.

Skin benefits

  • Best-characterised MSC secretome with proven regenerative factors
  • TGF-beta and IGF-1 support collagen production
  • Documented immunomodulatory effects beneficial for sensitive skin

Known concerns

  • EU Annex II/416 restriction
  • Bone marrow aspiration requires medical consent and screening
  • Pathogen screening from bone marrow source mandatory
  • FBS in culture medium requires animal by-product compliance

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Check your shelf

Find HUMAN BONE MARROW MESENCHYMAL STEM CELL CONDITIONED MEDIA in your products.

Scan any cosmetic product with LuxSense to see if it contains HUMAN BONE MARROW MESENCHYMAL STEM CELL CONDITIONED MEDIA and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.