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HUMAN CHORION CELL CONDITIONED MEDIA

42

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

The growth medium from cultured human placental membrane cells, containing secreted factors from pregnancy-related tissue.

Human chorion cell conditioned media is regulated under EU Annex II/416 as a material of human origin. The chorion is a fetal membrane component, making sourcing ethically sensitive. The secretome is undefined and may contain pregnancy-specific hormones or immunomodulatory factors requiring extensive characterisation. It is rarely used in commercial cosmetics in the EU due to these regulatory and ethical barriers.

Skin benefits

  • May contain broad spectrum of regenerative signals
  • Placental-origin factors historically associated with wound healing

Known concerns

  • EU Annex II/416 restriction
  • Undefined secretome including potential hormone contamination
  • Ethical concerns around fetal tissue sourcing
  • Batch variability from primary cell cultures

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.