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Skin Conditioning

HUMAN PLACENTAL PROTEIN

CAS -
12

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Protein extract from human placenta. EU-banned in cosmetics; US FDA warns against its use. Avoid.

Human placental protein refers to protein fractions derived from human placenta. The EU Cosmetics Regulation Annex II (entry 419) prohibits "cells, tissues or products of human origin" in cosmetic products. The US FDA has issued warning letters to companies marketing human placenta cosmetics and has identified associated hormonal content concerns (particularly oestrogen activity linked to premature puberty case reports). Beyond regulation, use of human-origin materials raises ethical, consent, provenance and infectious-disease transmission concerns (HIV, hepatitis viruses). No legitimate cosmetic justification.

Function

HAIR CONDITIONING, SKIN CONDITIONING

Skin benefits

  • No legitimate benefit given ethical and regulatory status

Known concerns

  • Human-tissue derived — banned in cosmetics in EU (Annex II entry 419 — human tissues and body products)
  • Infectious-disease transmission risk (blood-borne pathogens)
  • US FDA has issued warning letters for human-placenta cosmetics
  • Ethical, consent and provenance concerns

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related skin conditionings

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.