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HUMAN TONSIL MESENCHYMAL STEM CELL CONDITIONED MEDIA

46

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

The growth medium from cultured human palatine tonsil mesenchymal stem cells, containing immune tissue-derived signalling factors.

Human tonsil mesenchymal stem cell conditioned media falls under EU Annex II/416 restriction for materials of human origin. Tonsillar tissue is sourced from surgical waste (tonsillectomy) with appropriate consent. Tonsil-derived MSCs have documented immunomodulatory properties and secrete a distinct profile of cytokines and growth factors. The secretome is partially characterised but requires full safety evaluation under EU cosmetics regulation.

Skin benefits

  • Tonsil MSC secretome rich in immunomodulatory cytokines
  • May help modulate skin inflammation
  • Contains lymphoid tissue-derived growth factors

Known concerns

  • EU Annex II/416 restriction
  • Tonsil tissue is immune-rich — requires thorough pathogen screening
  • Donor consent from surgical patients required
  • Undefined secretome from lymphoid tissue

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.