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HUMAN UMBILICAL BLOOD DERIVED NATURAL KILLER CELL CONDITIONED MEDIA

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Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

The growth medium from cultured human umbilical cord blood natural killer cells, containing immune cell secretions with potential anti-tumour and immunomodulatory activity.

Human umbilical blood NK cell conditioned media falls under EU Annex II/416 for materials of human origin. Natural killer cells are immune lymphocytes that secrete cytokines including IFN-gamma, TNF-alpha and perforins. The secretome from NK cells is distinctly pro-inflammatory compared to MSC-conditioned media. Sourcing from cord blood requires compliance with blood establishment regulations and full donor screening.

Skin benefits

  • Contains IFN-gamma and other immune cytokines
  • NK cell factors may stimulate skin immune surveillance

Known concerns

  • EU Annex II/416 restriction
  • NK cell secretome is pro-inflammatory — may not suit sensitive skin
  • Blood-borne pathogen screening mandatory
  • Cord blood establishment compliance required

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.