Skin Conditioning
HUMAN UMBILICAL WHARTON'S JELLY MESENCHYMAL STEM CELL CONDITIONED MEDIA FILTRATE
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Filtered conditioned medium from cultured umbilical-cord stem cells. Same human-tissue regulatory and safety concerns as exosome ingredients.
Human umbilical Wharton's jelly mesenchymal stem cell conditioned media filtrate is the soluble, filtered fraction (growth factors, cytokines, peptides, microvesicles) collected from cultured human umbilical-cord MSCs. EU Regulation 1223/2009 Annex II restricts the use of human-derived materials in cosmetics, the US FDA may classify products with regenerative therapeutic claims as biologics, and donor screening, viral inactivation, sterility, and batch consistency are not standardised in cosmetics. There is no SCCS or CIR opinion; safety and efficacy rest on supplier dossiers.
Function
Skin benefits
- Marketed as growth-factor and cytokine source for regeneration
Known concerns
- Human-tissue derived — restricted under EU Regulation 1223/2009 Annex II
- Likely a US FDA biologic if therapeutic claims are made
- Sterility, viral, and donor-screening risks
- No SCCS or CIR cosmetic safety opinion
- Significant ethical sourcing concerns
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.