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Pharmaceutical Active

HYDROCORTISONE ACETATE

CAS 50-03-3
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A topical corticosteroid drug — banned from cosmetic products in the EU under Annex II. Powerful anti-inflammatory but causes skin thinning, dependence and rebound flares.

Function

SKIN CONDITIONING

Skin benefits

  • Strong anti-inflammatory in pharmaceutical use
  • OTC topical drug for eczema/dermatitis

Known concerns

  • EU Annex II — banned in cosmetics
  • Topical corticosteroid, skin-thinning with chronic use
  • Adrenal suppression possible with prolonged use
  • Rebound dermatitis on withdrawal
  • Steroid acne and rosacea aggravation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.