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hydrocortisone butyrate (USAN:BAN:JAN)

CAS 13609-67-1
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Hydrocortisone butyrate (USAN:BAN:JAN) is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

Hydrocortisone butyrate is a potent topical corticosteroid. It carries multiple EU CLP hazard classifications including H302, H315, H319, H341, H361, H373. Corticosteroids are prescription-only medicines in the EU and are not permitted in cosmetic products. Systemic absorption can cause skin atrophy, adrenal suppression, and other serious adverse effects.

Known concerns

  • Not approved for cosmetic use in EU
  • Topical corticosteroid with systemic toxicity
  • H361 reproductive toxicity
  • H341 mutagenicity concern
  • Skin atrophy with prolonged use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.