Banned skin-lightening agent
Hydroquinone methylether / Mequinol
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
Mequinol (hydroquinone methyl ether) is a tyrosinase inhibitor historically used for skin lightening. It is prohibited in EU cosmetics due to depigmentation disorders and metabolism to hydroquinone.
Skin benefits
- Historically used as a skin-lightening agent for hyperpigmentation
- Acts as a tyrosinase inhibitor reducing melanin production
Known concerns
- Banned in EU cosmetics under Annex II of Regulation 1223/2009
- Causes paradoxical hyperpigmentation and depigmentation disorders
- Metabolizes to hydroquinone with associated genotoxicity concerns
- Linked to confetti-like leukoderma with prolonged use
- Available only as a prescription drug in regulated markets
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.