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HYDROXYCORTISONE SUCCINATE

CAS 2203-97-6
30

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A corticosteroid ester derivative restricted in EU cosmetic products under Annex II.

Hydroxycortisone Succinate is the succinate ester of hydrocortisone, a naturally occurring glucocorticoid. Corticosteroids and their derivatives are restricted in cosmetic products under EU CosIng Annex II reference II/300 due to their pharmacological activity and potential for causing skin atrophy, telangiectasia, and systemic effects with prolonged topical application.

Known concerns

  • EU Annex II restriction (II/300)
  • Corticosteroid class concern
  • Skin atrophy with prolonged use
  • Potential systemic effects

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.