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Hydroxyzine (INN)

CAS 68-88-2
22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Hydroxyzine (INN) is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

Hydroxyzine is a first-generation antihistamine (piperazine class) used orally for anxiety and allergic conditions. It is classified as a pharmaceutical substance with no established safe use in cosmetic formulations and is prohibited under EU Annex II of Regulation (EC) No 1223/2009.

Known concerns

  • Pharmaceutical agent
  • EU Annex II banned
  • CNS depressant effects
  • Not evaluated for cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.