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Imidazolidine-2-thione (Ethylene thiourea)

CAS 96-45-7
18

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A thiourea derivative (ethylene thiourea) with severe reproductive toxicity and carcinogenicity concerns, banned from cosmetic applications in the EU.

Imidazolidine-2-thione (Ethylene thiourea, ETU) carries H360D (reproductive toxicity), H351 (carcinogen suspect), and H372 (specific organ toxicity) classifications, among many others. It is not listed in EU Annex II because it is already prohibited by its classification as a substance of very high concern (SVHC) due to reproductive toxicity. ETU is primarily used as a rubber accelerator and is prohibited in cosmetic products. The ingredient has no acceptable use in topical formulations due to its severe toxicity profile.

Known concerns

  • Reproductive toxicity (H360D)
  • Suspected carcinogen (H351)
  • Specific organ toxicity (H372)
  • Skin sensitizer (H317)
  • EU SVHC substance

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.