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Ketobemidone hydrochloride

CAS 5965-49-1
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Ketobemidone Hydrochloride is a cosmetic ingredient. Exercise caution due to limited available safety data.

Ketobemidone is a potent synthetic opioid analgesic approximately equipotent to morphine. The hazard profile includes H301/H302 (acute toxicity), H315 (skin irritation), H319 (eye irritation), H331 (toxic if inhaled), and H335 (respiratory irritation). Listed in EU Annex II (banned substances), it may not be used in cosmetic products at any significant concentration. The opioid classification alone makes it entirely unsuitable for cosmetic formulations.

Known concerns

  • EU Annex II banned at >=0.1%
  • Potent opioid analgesic
  • H301/H302/H331 acute toxicity
  • Narcotic pharmacological activity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.