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megestrol

CAS 3562-63-8
4

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Megestrol is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Megestrol acetate is a synthetic progestogen related to medroxyprogesterone acetate, used therapeutically as an appetite stimulant and in hormone replacement therapy. Under EU Regulation (EC) No 1223/2009, hormonal substances with pharmaceutical activity are listed in Annex II as prohibited cosmetic ingredients. The ingredient has no CosIng entry as a permitted cosmetic substance, and hormonal agents of this type are specifically excluded from cosmetic use due to their systemic pharmacological effects.

Known concerns

  • Synthetic progestogen — prohibited in cosmetics (EU Annex II)
  • Hormonal/pharmaceutical activity incompatible with cosmetic regulation
  • No cosmetic safety assessment available

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.