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Metaproterenol sulfate [USAN]

CAS 5874-97-5
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A prescription bronchodilator drug not permitted in cosmetic products due to its pharmacological activity and potential cardiovascular effects.

Metaproterenol sulfate is a synthetic catecholamine that acts primarily on beta-2 adrenergic receptors to relax bronchial smooth muscle. In the EU, substances with pharmacological activity are generally prohibited in cosmetic products under Regulation (EC) No 1223/2009. The H332 hazard statement (harmful if inhaled) and its status as a US-approved drug substance indicate significant safety concerns for dermal exposure.

Known concerns

  • Pharmacologically active substance not permitted in EU cosmetics
  • H332 acute inhalation toxicity
  • Potential cardiovascular effects at systemic exposure
  • Not evaluated for cosmetic use safety

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.