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Metformin (INN) and its salts

CAS 657-24-9
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Metformin (inn) And Its Salts is a cosmetic ingredient. Exercise caution due to limited available safety data.

Metformin's INN status identifies it as a medicine with systemic pharmacological action. Under EU cosmetics law, substances classified as medicines are excluded from cosmetic use if they act pharmacologically on the skin rather than merely aesthetically. The EU Commission has confirmed that anti-diabetic drugs like metformin are prohibited cosmetic ingredients regardless of concentration. The H302/H315/H319 classifications confirm mild topical irritancy, but the primary concern is pharmacological.

Known concerns

  • EU cosmetics prohibition: pharmacologically active medicine (INN)
  • CMR classification as medicine irrespective of cosmetic intent
  • H302/H315/H319: irritancy

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.