Skip to content

NICOTINOYL TRIPEPTIDE-1

CAS -
82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A niacin-modified peptide combining nicotinic acid with a tripeptide sequence, used in anti-aging skincare for skin brightening and firming.

Nicotinoyl Tripeptide-1 is a modified peptide where nicotinic acid (niacin/vitamin B3) is conjugated to a tripeptide sequence. The combination of niacin (vitamin B3) with a collagen-stimulating peptide provides dual action for skin brightening and anti-aging. Niacin derivatives are well-established in cosmetics for their skin-brightening and barrier-strengthening effects. The peptide component may support collagen synthesis. The EU Cosmetics Regulation 1223/2009 does not specifically restrict this ingredient. Nicotinoyl tripeptide-1 is synthesized with high purity and is considered safe for cosmetic use. Niacin can cause vasodilation (flushing) in sensitive individuals, but this is typically associated with higher concentrations.

Skin benefits

  • Skin brightening from niacin component
  • Anti-aging and collagen support
  • Improves skin tone and radiance

Known concerns

  • May cause flushing in very sensitive individuals
  • Niacin content at low levels generally well-tolerated

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Check your shelf

Find NICOTINOYL TRIPEPTIDE-1 in your products.

Scan any cosmetic product with LuxSense to see if it contains NICOTINOYL TRIPEPTIDE-1 and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.