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Oxymetazoline hydrochloride [USAN:JAN]

CAS 2315-02-8
32

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Oxymetazoline Hydrochloride [usan:jan] is a cosmetic ingredient. Exercise caution due to limited available safety data.

Oxymetazoline is a selective alpha-1 adrenergic agonist used as a topical decongestant. It carries H300 (fatal if swallowed), H318 (causes serious eye damage), H330 (fatal if inhaled), H372 (organ damage), and H412 (aquatic toxicity). While it has legitimate pharmaceutical use in nasal decongestants, the combination of acute toxicity and pharmacological activity makes it unsuitable for cosmetic formulations.

Known concerns

  • Alpha-1 adrenergic agonist
  • Acute oral toxicity (H300)
  • Serious eye damage (H318)
  • Inhalation toxicity (H330)
  • Organ toxicity (H372)
  • Not approved for cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.