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PEG-444 PENTAERYTHRITYL TETRA(GLUTAROYLSUCCINIMIDE)

CAS -
70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A high-molecular-weight polymer used as a binder in cosmetics, generally safe though PEG component raises minor contamination concerns.

PEG-444 PENTAERYTHRITYL TETRA(GLUTAROYLSUCCINIMIDE) is a polyethylene glycol grafted polymer with pentaerythritol core and glutaroyl/succinimide functionality, used as a binder and film-former. No GHS hazard statements are listed. The PEG-444 designation indicates approximately 444 ethylene glycol units, which raises the standard PEG contamination concern (1,4-dioxane and ethylene oxide residuals). High-molecular-weight polymers generally do not penetrate the skin barrier. The ingredient does not appear on EU Annex II prohibition list. Residual monomers from the glutaroyl/succinimide components may cause irritation in highly sensitive individuals. Overall considered safe for cosmetic use at typical concentrations.

Skin benefits

  • Binder improves product integrity
  • Film-forming enhances wear characteristics

Known concerns

  • PEG contamination concern (1,4-dioxane, ethylene oxide)
  • Potential residual monomer irritation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.