Emollient
PENTAHYDROSQUALENE
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A partially hydrogenated form of squalene — a light, skin-mimetic emollient with improved stability over native squalene. Generally well-tolerated.
Pentahydrosqualene (CAS 68629-07-2) is squalene that has had five of its six double bonds hydrogenated, leaving a single double bond. The result is a light, dry-feel emollient much more oxidation-stable than native squalene while still skin-mimetic. It is commonly plant-derived (olive, sugarcane fermentation, or amaranth) but historically some sources used shark liver oil — buyers should request source documentation. CIR has reviewed squalene/squalane chemistry as safe for cosmetic use. No CMR, endocrine, or significant GHS hazards reported; well-tolerated and non-comedogenic at typical use levels.
Function
Skin benefits
- Lightweight, skin-mimetic emollient
- More oxidation-stable than squalene
- Soft, dry skin feel
Known concerns
- Source disclosure varies (plant vs animal)
- Limited compound-specific clinical data
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related emollients
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.