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Solvent

PERFLUOROBUTYLCYCLOHEXANE

CAS 374-60-7
32

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A fully fluorinated hydrocarbon — part of the PFAS family now being banned from cosmetics worldwide for environmental persistence.

Perfluorobutylcyclohexane (CAS 374-60-7) is a fully fluorinated cyclic hydrocarbon belonging to the broader per- and polyfluoroalkyl substances (PFAS) family. PFAS are characterized by extreme persistence in the environment ("forever chemicals"), bioaccumulation, and increasing regulatory restriction. The EU, California, Maine, Minnesota, and several other jurisdictions have enacted or are enacting cosmetic PFAS bans. Even where not yet prohibited, PFAS are strongly disfavored. This specific molecule shares the PFAS persistence profile. While acute toxicity is low, the broader environmental and policy profile makes it inappropriate for modern cosmetic formulation.

Function

ANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

Skin benefits

  • Perfluorinated solvent with unusual carrier properties
  • Historically used in specialty cosmetic applications

Known concerns

  • Perfluorinated compound (PFAS family) — persistent environmental pollutant
  • PFAS are subject to growing global cosmetic bans
  • Bioaccumulative and resistant to environmental degradation
  • EU and several US states moving toward full cosmetic PFAS bans
  • Not recommended for current cosmetic formulation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related solvents

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.