Skip to content

Skin Conditioning

PETASITES JAPONICUS LEAF EXTRACT

CAS 91845-41-9 Updated
30

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Japanese butterbur (Petasites) leaf extract (CAS 91845-41-9) — contains hepatotoxic pyrrolizidine alkaloids (IARC Group 2B). Without rigorous PA removal, cosmetic use raises serious safety concerns.

Function

SKIN CONDITIONING - EMOLLIENT

Skin benefits

  • Sesquiterpene antioxidants
  • Traditional anti-inflammatory use
  • Phenolic compounds

Known concerns

  • Petasites contains pyrrolizidine alkaloids — hepatotoxic and IARC Group 2B carcinogen
  • EU and BfR limit PA exposure to <0.007 ug/kg/day
  • Severe liver injury documented from Petasites
  • Only PA-free standardized extracts considered acceptable
  • Not recommended for cosmetic use without rigorous PA removal

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related skin conditionings

30
(R,S)-2-Amino-3,3-dimethylbutane amide
Skin Conditioning
 30
ACORUS CALAMUS RHIZOME EXTRACT
Skin Conditioning
 30
ARECA CATECHU SEED EXTRACT
Skin Conditioning
 30
ARECA CATECHU SEED/EUGENIA CARYOPHYLLUS STEM EXTRACT
Skin Conditioning
 30
CAPSAICIN
Skin Conditioning
 30
DICTAMNUS DASYCARPUS ROOT EXTRACT
Skin Conditioning
 30
DRYOPTERIS CRASSIRHIZOMA ROOT EXTRACT
Skin Conditioning
 30
DUCK EMBRYO EXTRACT
Skin Conditioning

Check your shelf

Find PETASITES JAPONICUS LEAF EXTRACT in your products.

Scan any cosmetic product with LuxSense to see if it contains PETASITES JAPONICUS LEAF EXTRACT and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.