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Fragrance

PIPER NIGRUM SEED

CAS 84929-41-9
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Black pepper seed — pungent piperine gives warming effects but also makes this a known irritant, so it belongs in the orange band.

Piper nigrum (black pepper) seed, as oil or extract, contains piperine, piperidine, and volatile terpenes (limonene, beta-caryophyllene, sabinene). It is used for aromatic, warming, and traditional skin-stimulating claims. Listed in EU CosIng; no SCCS positive opinion for leave-on at high concentration. Piperine is a known TRPV1 agonist and mucosal/skin irritant at meaningful concentrations, and the essential oil has documented sensitisation and phototoxic potential, especially near eyes and on damaged skin. Several of its volatiles are Annex III fragrance allergens. Evidence is moderate — mechanism is well characterised, cosmetic-specific risk/benefit is clear.

Skin benefits

  • Piperine antioxidant/warming action
  • Aromatic character

Known concerns

  • Skin and mucosal irritation from piperine
  • EU-listed fragrance allergen content
  • Avoid near eyes/broken skin
  • Potential phototoxicity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.