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Prednisolone

CAS 50-24-8
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Prednisolone is a cosmetic ingredient. Raw material may pose reproductive safety concerns. Exercise caution due to limited available safety data.

Prednisolone is a synthetic glucocorticoid approximately 4-5 times more potent than hydrocortisone. It carries extensive hazard statements including H302/H332 (acute toxicity), H360/H361 (reproductive/developmental toxicity), H372/H373 (organ toxicity), and H411 (aquatic toxicity). EU SCCS guidance indicates corticosteroids are not approved for cosmetic use. These are prescription-only medicines in most EU member states.

Known concerns

  • Synthetic glucocorticoid - prescription only
  • Reproductive toxicity concern (H360)
  • Organ toxicity (H372)
  • Aquatic toxicity (H411)
  • Not authorized in EU cosmetics

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.