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Banned Amine Class

Secondary alkyl- and alkanolamines and their salts

CAS 111-42-2 / 110-97-4
4

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Secondary alkylamines and alkanolamines like DEA are prohibited in EU cosmetics because they readily form carcinogenic nitrosamines. They have no permitted use in finished cosmetic or personal care products.

Skin benefits

  • Used in industrial chemistry as pH adjusters outside cosmetics
  • Regulatory clarity through Annex II listing simplifies compliance

Known concerns

  • EU Annex II prohibited substances in cosmetics
  • Form carcinogenic N-nitrosamines when combined with nitrosating agents
  • Diethanolamine (DEA, 111-42-2) and diethylamine are restricted intermediate chemicals
  • Skin and eye irritants on direct contact

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.