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STAPHYLOCOCCUS AUREUS BACTERIOPHAGE 27

45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A bacteriophage preparation used as an antimicrobial agent; while bacteriophages are promising for topical antimicrobial applications, their use in EU cosmetics is novel and requires careful safety evaluation.

Staphylococcus Aureus Bacteriophage 27 is a bacteriophage (virus that infects bacteria) replicated in Staphylococcus aureus. Bacteriophage technology is emerging in cosmetics for targeted antimicrobial applications, particularly for acne-prone skin. However, this is a very novel cosmetic ingredient category in the EU. Not specifically listed in EU Regulation 1223/2009 Annex II or III, but the regulatory status of bacteriophages in cosmetics is not well-established. Safety concerns include potential immune response to phage particles, lysogenic conversion risks, and precise strain identification requirements.

Skin benefits

  • Targeted antimicrobial activity against S. aureus
  • Potential acne treatment applications
  • Alternative to traditional preservatives

Known concerns

  • Very novel cosmetic ingredient with limited safety data
  • Potential immune response to phage particles
  • Regulatory status in EU cosmetics not well-defined
  • Strain-specific safety considerations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.