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Pharmaceutical antibiotic (prohibited)

Sulfadiazine

CAS 68-35-9
12

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A sulfonamide antibiotic prohibited from cosmetic use in the EU. Reserved for prescription medicine, with significant allergy, photosensitivity, and antimicrobial-resistance concerns.

Skin benefits

  • Has prescription pharmaceutical use as an antibacterial sulfonamide
  • Used in burn ointments under medical supervision only

Known concerns

  • Prohibited cosmetic ingredient under EU Regulation 1223/2009 Annex II (antibiotic)
  • GHS H317 may cause allergic skin reaction and H334 respiratory sensitization
  • Can trigger severe sulfa allergy and Stevens-Johnson syndrome
  • Photosensitization and contact dermatitis risk
  • Antimicrobial resistance concern with non-medical use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.