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TDI OXIDIZED MICROCRYSTALLINE CERA

58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

The same TDI-modified microcrystalline wax as entry 32628 — toluene diisocyanate chemistry introduces potential respiratory and skin sensitization concerns that make this unsuitable for leave-on skin applications.

TDI Oxidized Microcrystalline Cera is the INCI name variant referring to the same reaction product as entry 32628: oxidized microcrystalline wax reacted with toluene diisocyanate (TDI). The ingredient contains free and bound isocyanate groups that can react with skin proteins to form antigens, potentially causing allergic contact dermatitis. Under GHS classification, TDI itself is H332 (inhalation hazard) and H317 (skin sensitization). The oxidized wax matrix does not eliminate this risk and may even facilitate skin penetration of reactive TDI fragments.

Known concerns

  • Skin sensitization from isocyanate-protein adducts
  • Respiratory hazard if aerosolized during formulation
  • Same concerns as TDI itself in cosmetic context
  • Not appropriate for leave-on skin care

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.