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Banned/Restricted

Tretinoin (INN) (retinoic acid and its salts)

CAS 302-79-4 Updated
4

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Tretinoin (all-trans retinoic acid) is an EU Annex II banned substance in cosmetics. It is a teratogen and CMR Cat 1B carcinogen, restricted strictly to prescription dermatology pharmaceuticals.

Skin benefits

  • Primarily a processing aid

Known concerns

  • EU Annex II prohibited substance in cosmetics
  • Teratogen — causes birth defects
  • CMR Category 1B classification
  • Severe skin irritation
  • Prescription pharmaceutical only

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related banned/restricteds

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.