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Trichloroethylene

CAS 79-01-6
6

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Trichloroethylene is a cosmetic ingredient. Exercise caution due to limited available safety data.

Trichloroethylene (CAS 79-01-6, TCE) is a chlorinated solvent that was previously used in cosmetic formulations including nail polish removers and degreasing agents. EU Regulation 1223/2009 Annex II prohibits the use of this substance in cosmetic products. The compound carries extensive hazard statements including H315 (causes skin irritation), H319 (causes serious eye irritation), H336 (may cause drowsiness or dizziness), H341 (suspected of causing genetic defects), H350 (may cause cancer), H361 (suspected of damaging fertility or unborn child), and H372 (causes damage to organs through prolonged or repeated exposure). TCE is classified as a Group 1 carcinogen by IARC.

Known concerns

  • EU Annex II banned - Group 1 IARC carcinogen
  • Confirmed carcinogen (H350)
  • Suspected mutagen (H341)
  • Neurotoxicity and CNS depression (H336)
  • Organ toxicity from repeated exposure (H372)
  • Reproductive toxicity (H361)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.