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Restricted chelator

Trisodium nitrilotriacetate

CAS 5064-31-3
22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A powerful chelating agent classified as possibly carcinogenic by IARC and restricted in EU cosmetics. Safer chelators like EDTA salts or GLDA are typically preferred for personal care.

Skin benefits

  • Strong chelator for hard water ions in cleansers
  • Improves surfactant performance
  • Useful in industrial cleaning formulations

Known concerns

  • Classified IARC Group 2B, possibly carcinogenic to humans
  • Restricted or banned in cosmetics in the EU under CLP/CosIng
  • Kidney and urinary tract effects in animal studies
  • Persistent in wastewater with environmental impact

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.