Urginea scilla Steinh. and its galenical preparations
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A cosmetic ingredient. Exercise caution due to limited available safety data.
Urginea scilla (sea squill) contains cardiac glycosides including scillarenin that affect cardiac rhythm by inhibiting Na+/K+ ATPase. EU Regulation 1223/2009 Annex II prohibits the use of this plant material and its galenical preparations in cosmetic products due to the narrow margin between therapeutic and toxic doses. Ingestion of small amounts can cause serious cardiac arrhythmias, and cutaneous absorption of cardiac glycosides poses significant risk especially in individuals with cardiac conditions.
Known concerns
- EU Annex II banned - toxic plant material
- Cardiac glycoside content causes serious arrhythmias
- Narrow therapeutic index - risk of fatal poisoning
- No safe concentration for cosmetic use
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.