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Antioxidant

ZEAXANTHIN

CAS 144-68-3
85

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A carotenoid antioxidant found naturally in corn, egg yolks and leafy greens. Excellent antioxidant safety profile; mainly concerned with formulation color.

Zeaxanthin (CAS 144-68-3) is a xanthophyll carotenoid naturally present in corn, eggs, and green leafy vegetables, and is one of the two primary macular pigments in the human retina. In cosmetics it functions as an antioxidant, protecting against oxidative stress from UV and blue light. It has extensive food-grade and nutraceutical safety data including EFSA review for dietary use. No IARC classification, no GHS hazard pictograms at cosmetic use levels, and no reproductive/developmental toxicity flags. Main formulation limitations are its yellow-orange color and oxidative instability, which often require encapsulation or stabilization.

Function

ANTIOXIDANT

Skin benefits

  • Carotenoid antioxidant with strong free-radical quenching
  • Supports skin photoprotection against blue light/UV oxidative stress
  • Food-grade safety precedent from dietary supplements

Known concerns

  • Can stain formulations yellow-orange
  • Oxidatively unstable without proper encapsulation
  • Limited topical-specific clinical trials

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.