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Antiperspirant

ZIRCONIUM CHLOROHYDRATE

CAS 18428-88-1
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A zirconium-based antiperspirant salt — prohibited by the US FDA in aerosol products and heavily restricted elsewhere. Avoid in modern formulation.

Zirconium chlorohydrate (CAS 18428-88-1) is a zirconium-based astringent historically used in antiperspirants. The US FDA prohibits zirconium-containing compounds in aerosol deodorants and antiperspirants due to lung granuloma cases reported in the 1970s. EU regulation 1223/2009 Annex III imposes strict restrictions on zirconium in cosmetics. In non-aerosol stick or roll-on forms, zirconium complexes (particularly aluminum-zirconium chlorohydrate complexes) remain used but are increasingly replaced by aluminum-only actives or aluminum-free alternatives due to consumer and regulatory pressure. The prior database score of 82 was substantially too generous.

Function

ASTRINGENT

Skin benefits

  • Strong astringent and antiperspirant activity
  • Efficient sweat-duct occlusion when formulated for aerosol or stick use

Known concerns

  • US FDA prohibits zirconium compounds in aerosol deodorants/antiperspirants
  • Zirconium compounds historically linked to granuloma formation
  • EU requires restrictive conditions for any zirconium use
  • Inhalation risk if aerosolized
  • Broadly disfavored for modern cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related antiperspirants

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.