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2-[2-(dimethylammonio)propyl]-1-oxo-2,2-diphenylethyl]ammonium sulphate

CAS 35144-63-9
32

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An amino-ketone local anesthetic derivative that is restricted in EU cosmetics due to sensitization and pharmaceutical concerns.

This diphenyl-substituted amino-ketone compound is structurally related to local anesthetics and is restricted under EU Annex III of Regulation EC 1223/2009. The dimethylammonio group and diphenylketone structure are associated with sensitization potential. Local anesthetics of this class have been progressively removed from cosmetic formulations in the EU due to their pharmaceutical classification and contact allergy risk.

Known concerns

  • EU Annex II/III restricted — not permitted in cosmetic products
  • Known sensitization potential as a local anesthetic derivative
  • Pharmaceutical classification — inappropriate for cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.